A Colour Reaction for Aromatic Amidines

The estimation of aromatic amidines.

The determination of aromatic amidines in plasma and urine.

Certain aromatic amidines have been reported to be useful chemotherapeutic agents for the treatment of leishmaniasis, trypanosomiasis, and babesiasis (1). Pharmacological and clinical studies of these compounds have been handicapped by lack of suitable methods for the determination of aromatic amidines in plasma and urine. Recently Fuller (2) described a method which is based upon a reaction be...

Viii. a Specific Colour Reaction for Ergosterol

THE unique function of ergosterol as the parent substance of vitamin D made it desirable to find a colour reaction for it, by means of which it could be detected in the presence of other sterols. In searching for such a reaction, the property of formaldehyde of shifting the colour from the red into the blue part of the spectrum in the usual colour reactions of sterols [Whitby, 1923; Rosenheim, ...

Simple colour reaction for alkaptonuria.

The aromatic ene reaction

The ene reaction is a pericyclic process in which an alkene with an allylic hydrogen atom (the ene donor) reacts with a second unsaturated species (the enophile) to form a new product with a transposed π-bond. The aromatic ene reaction, in which the alkene component is embedded in an aromatic ring, has only been reported in a few (four) instances and has proceeded in low yield (≤6%). Here, we s...